Matlalo le lipeo tsa morara le monokotšoai li na le resveratrol, e leng se etsang hore veine e khubelu e be ngata ka har'a motsoako ona. Lipatlisiso li bontša hore e na le melemo e mengata ea bophelo bo botle, empa u lokela ho tseba haholoanyane ka hore na u lokela ho nka tlatsetso e kae.
Haeba u utloile hore veine e khubelu e thusa ho theola k'holeseterole, mohlomong u kile ua utloela ka resveratrol, motsoako oa semela o sebelisoang haholo veine e khubelu.
Empa ntle le ho ba karolo e ntle ea veine e khubelu le lijo tse ling, resveratrol e boetse e na le bokhoni ba bophelo bo botle.
Ebile, li-supplement tsa resveratrol li amahanngoa le melemo e mengata e makatsang ea bophelo bo botle, ho kenyelletsa ho sireletsa ts'ebetso ea boko le ho theola khatello ea mali (1, 2, 3, 4).
Sengoliloeng sena se hlalosa seo u hlokang ho se tseba ka resveratrol, ho kenyelletsa le melemo ea eona e supileng e kaholimo ho bophelo bo botle.
Resveratrol ke motsoako oa semela o sebetsang joalo ka antioxidant. Mehloli e meholo ea lijo e kenyelletsa veine e khubelu, morara, monokotsoai le matokomane (5, 6).
Motsoako ona o atisa ho tsepamisa mohopolo matlalong le peo ea morara le monokotsoai. Likarolo tsena tsa morara li kenya letsoho ho belisoa ha veine e khubelu 'me ka hona li na le "resveratrol" e ngata haholo (5, 7).
Leha ho le joalo, liphuputso tse ngata tsa resveratrol li entsoe liphoofolong le ka har'a li-tubes tsa teko ho sebelisa boholo ba motsoako ona (5, 8).
Lithutong tse fokolang ho batho, boholo ba tsona li tsepamisitse maikutlo mefuteng e ekelitsoeng ea motsoako, e fumanehang maemong a holimo ho feta a fumanoang lijong (5).
Resveratrol ke motsoako oa antioxidant o fumanoang veineng e khubelu, monokotsoai le matokomane. Lithuto tse ngata tsa batho li sebelisitse li-supplement tse nang le maemo a phahameng a resveratrol.
Ka lebaka la thepa ea eona ea antioxidant, resveratrol e kanna ea ba tlatsetso e ts'episang ho theola khatello ea mali (9).
Tlhahlobo ea 2015 e fihletse qeto ea hore litekanyetso tse phahameng li ka thusa ho fokotsa khatello ea maikutlo maboteng a methapo ea pelo ha pelo e otla (3).
Khatello ena e bitsoa khatello ea mali ea systolic 'me e hlaha e le palo e phahameng ho palo ea khatello ea mali.
Khatello ea mali ea systolic hangata e eketseha ka lilemo ka lebaka la atherosclerosis. Ha e phahame, ke kotsi ea lefu la pelo.
Resveratrol e ka fihlela litlamorao tsa ho theola khatello ea mali ka ho thusa ho hlahisa nitric oxide e ngata, e etsang hore methapo ea mali e phomole (10, 11).
Leha ho le joalo, bangoli ba thuto ba boletse hore lipatlisiso tse ling lia hlokahala ho etsa likhothaletso tse tobileng mabapi le tekanyo e nepahetseng ea resveratrol bakeng sa litlamorao tse ngata khatellong ea mali.
Lithuto tse 'maloa tsa liphoofolo li bontšitse hore li-supplement tsa resveratrol li ka fetola lipids tsa mali ka mekhoa e phetseng hantle (12, 13).
Phuputsong ea 2016, litoeba li ile tsa feptjoa lijo tse nang le protheine e ngata le mafura a polyunsaturated a tlatsitsoeng ka resveratrol.
Bafuputsi ba fumane hore karolelano ea kakaretso ea k'holeseterole le boima ba 'mele ba litoeba li fokotsehile, ha boemo ba "cholesterol" e ntle ea HDL bo eketseha (13).
Resveratrol e bonahala e ama maemo a k'holeseterole ka ho fokotsa ts'ebetso ea li-enzyme tse laolang tlhahiso ea k'holeseterole (13).
E le antioxidant, e boetse e fokotsa k'holeseterole e "mpe" ea LDL. Oxidation ea LDL e lebisa ho thehoeng ha letlapa leboteng la arterial (9, 14).
Kamora likhoeli tse ts'eletseng tsa kalafo, bankakarolo ba nkileng sekhechana sa morara o sa tebang kapa placebo ba bile le phokotso ea 4.5% ea LDL le phokotso ea 20% ho LDL e nang le oxidized (15).
Lisebelisoa tsa Resveratrol li ka ntlafatsa maemo a lipid a mali ho liphoofolo. Kaha ke antioxidant, li boetse li fokotsa oxidation ea LDL cholesterol.
Bokhoni ba komporo ea ho lelefatsa bophelo ba lintho tse fapaneng e se e le sebaka se seholo sa lipatlisiso (16).
Ho na le bopaki ba hore resveratrol e kenya tšebetsong liphatsa tsa lefutso tse itseng, ka hona e thibela mafu a botsofali (17).
Sena se sebetsa ka tsela e ts'oanang le thibelo ea khalori, e bontšitseng liphello tse tšepisang ho eketsa nako ea bophelo ka ho fetola tsela eo liphatsa tsa lefutso li hlahisoang ka eona (18, 19).
Tlhahlobo ea liphuputso tse hlahlobang sehokelo sena li fumane hore resveratrol e lelefatsa nako ea bophelo ho 60% ea lintho tse phelang tse ithutoang, empa phello e ne e bonahala haholo linthong tse sa amaneng haufi le batho, joalo ka liboko le litlhapi (20).
Liphuputso tsa liphoofolo li bontšitse hore li-supplement tsa resveratrol li ka eketsa nako ea bophelo. Leha ho le joalo, ha ho hlake hore na li tla ba le phello e tšoanang ho batho.
Liphuputso tse 'maloa li bonts'itse hore ho noa veine e khubelu ho ka thusa ho fokotseha ha kelello ho amanang le botsofali (21, 22, 23, 24).
E bonahala e kena-kenana le likhechana tsa protheine tse bitsoang amyloid beta, tse bohlokoa ho thehoeng ha matšoao a lefu la Alzheimer's (21, 25).
Le ha lipatlisiso tsena li khahla, bo-ramahlale ba ntse ba e-na le lipotso mabapi le bokhoni ba 'mele ba ho sebelisa resveratrol e eketsehileng, ho fokotsa tšebeliso ea eona hanghang joalo ka tlatsetso e sireletsang boko (1, 2).
Resveratrol ke motsoako o matla oa antioxidant le o khahlanong le ho ruruha o ka sireletsang lisele tsa boko ho senya.
Melemo ena e kenyelletsa ho ntlafatsa kutloisiso ea insulin le ho thibela mathata a lefu la tsoekere (26,27,28,29).
Tlhaloso e 'ngoe ea hore na resveratrol e sebetsa joang ke hore e ka thibela enzyme ho fetola tsoekere hore e be sorbitol, joala bo tsoekere.
Ha sorbitol e ngata haholo e bokellana 'meleng ea batho ba nang le lefu la tsoekere, e ka baka khatello ea oxidative e senyang lisele (30, 31).
Resveratrol e kanna ea tsoela batho ba nang le lefu la tsoekere molemo ho feta batho ba se nang lefu la tsoekere. Thutong e 'ngoe ea liphoofolo, veine e khubelu le resveratrol li fumanoe li le matla ho feta litoeba tsa lefu la tsoekere ho feta litoeba tsa nondiabetic (32).
Bafuputsi ba re motsoako ona o ka sebelisoa ho phekola lefu la tsoekere le mathata a lona nakong e tlang, empa lipatlisiso tse ling li hlokahala.
Resveratrol e thusa litoeba ho ntlafatsa kutloisiso ea insulin le ho loants'a mathata a lefu la tsoekere. Nakong e tlang, bakuli ba nang le lefu la tsoekere le bona ba ka rua molemo kalafong ea resveratrol.
Litlama tsa litlama li ntse li ithutoa e le mokhoa oa ho phekola le ho thibela bohloko ba manonyeletso. Ha e nkoa e le tlatsetso, resveratrol e ka thusa ho sireletsa lefufuru ho tloha ho senyeha (33, 34).
Phuputso e 'ngoe e kentse resveratrol manonyeletsong a mangole a mebutlanyana ea arthritic mme ea fumana hore mebutlanyana ena e na le tšenyo e nyane ea lefufuru (34).
Liphuputso tse ling tsa liteko le liphoofolo li bontšitse bokhoni ba motsoako ona oa ho fokotsa ho ruruha le ho thibela tšenyo e kopanetsoeng (33, 35, 36, 37).
Resveratrol e ithutiloe ka bokhoni ba eona ba ho thibela le ho phekola mofetše, haholo li-tubes tsa liteko. Leha ho le joalo, liphetho li tsoakane (30, 38, 39).
Ho bontšitsoe ho loantša mefuta e fapaneng ea lisele tsa mofetše lithutong tsa li-tube tsa liphoofolo le liteko, ho kenyeletsoa mpa, colon, letlalo, matsoele le mofetše oa prostate (40, 41, 42, 43, 44).
Leha ho le joalo, kaha lithuto ho fihlela joale li entsoe ka li-tubes tsa liteko le liphoofolong, ho hlokahala lipatlisiso tse eketsehileng ho utloisisa hore na motsoako ona o ka sebelisoa joang ho phekola mofetše bathong.
Lithuto tse sebelisang li-supplement tsa resveratrol ha li fumane likotsi tse kholo. Li bonahala li mamelloa hantle ke batho ba phetseng hantle (47).
Leha ho le joalo, hoa lokela ho hlokomeloa hore hajoale ho na le khaello ea likhothaletso tse felletseng mabapi le hore na motho o lokela ho nka resveratrol e kae ho fumana melemo ea bophelo bo botle.
Hape ho na le litemoso tse ling, haholo-holo mabapi le hore na resveratrol e sebelisana joang le meriana e meng.
Hobane litekanyetso tse phahameng li bontšitsoe ho thibela mali ho thibela mali ka har'a li-tubes tsa teko, li ka eketsa ho tsoa mali kapa maqeba ha li nkoa ka li-anticoagulants tse kang heparin kapa warfarin, kapa meriana e itseng ea bohloko (48, 49).
Resveratrol e boetse e thibela li-enzyme tse thusang ho tlosa metsoako e itseng 'meleng. Sena se bolela hore meriana e meng e ka fihla maemong a sa sireletsehang. Tsena li kenyelletsa lithethefatsi tse ling tse theolang khatello ea mali, lithethefatsi tse thibelang ho tšoenyeha, le li-immunosuppressants (50).
Haeba hona joale u noa meriana, u ka 'na ua batla ho bua le ngaka ea hau pele u noa resveratrol.