1. Bahanyetsi ba Endothelin

E ntšitsoe ho European herb chamomile, e ka hanyetsang endothelin le ho thibela tlhahiso ea melanocyte.Kabo e sa leka-lekaneng ea endothelin letlalong ke eona ntho e ka sehloohong e lebisang ho thehoeng ha pigmentation.Bahanyetsi ba Endothelin ba ka thibela endothelin.. tyrosinase le ho khothalletsa phapang ea melanocyte.

Liphuputso li fumane hore bahanyetsi ba endothelin ba ntšitsoeng linthong tse phelang metsing ba na le cytotoxicity e tlaase 'me ba ka thibela phapang ea endothelin ho melanocyte le mosebetsi oa tyrosinase.Mafu a letlalo a hyperpigmentation a bakoang ke ho eketseha -l e ka ba le menyetla ea kopo.

2. Resveratrol le lihlahisoa tsa eona

Resveratrolhaholo-holo e teng morara, Polygonum cuspidatum, Veratrum le limela tse ling, 'me e thibela mosebetsi oa melanocyte le mosebetsi oa tyrosinase ka mokhoa o itšetlehileng ka mahloriso, kahoo e fokotsa motsoako oa melanin.Jeong et al o fumane hore e boetse e amahanngoa le liprotheine tse amanang le tyrosinase ho melanogenesis.

Jia Lili le liphuputso tse ling li bontšitse hore topical resveratrol e ka ntlafatsa 'mala oa letlalo ka katleho, e na le phello e itseng e tšoeu,' me ha e na liphello tse mpe.Resveratrol e na le bofokoli ba ho se tsitse le bofokoli ba bioavailability.Liphuputso li fumane hore li-derivatives tsa eona (li-derivatives tsa pentaalkyl ether le tse nkiloeng ho tetraester) li na le bioavailability e phahameng 'me li ka thibela hamolemo tlhahiso ea melanin.E na le menyetla e pharaletseng ea ts'ebeliso ea litlolo tse soeufatsang.

3. Camellia Extract

Camellia ke mofuta oa Camellia oa lelapa la Camellia.Nakamura et al.e fumane hore camellia bud bud extract e ka thibela tlhahiso ea melanin le ho khothalletsa phapang ea fibroblast.Huang Xiaofeng le liphuputso tse ling li fihletse qeto ea hore lekala la tee la Dianshan le lekhasi la makhasi le molemo ho feta arbutin mabapi le ho ata ha lisele le ho thibela tšebetso ea tyrosinase, 'me le na le thepa e molemo ho feta arbutin.Ke mofuta o mocha oa ho hloekisa letlalo 'me o na le mefuta e mengata ea lisebelisoa.tebello.

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1. Arbutin

Ke inhibitor ea bohlokoa ea tyrosinase, e ka thibelang ts'ebetso ea tyrosinase, ea thibela tlhahiso ea dopa le dopaquinone, ka hona e thibela tlhahiso ea melanin, hape e ka fokotsa haholo pigmentation e bakoang ke mahlaseli a ultraviolet, empa e tsitsitse Ts'ebetso e mpe, ka tse ling. photosensitivity.

Phuputso e fumane hore arbutin e nang le motsoako oa 3% e na le thepa e ntle, cytotoxicity e tlaase, ho teneha le ho kula, 'me moeli o ka holimo oa khatello ea eona o ke ke oa feta 7%.Arbutin e ngata e tla senya letlalo le tloaelehileng.Sejo sa eona sa tlhaho se sebetsang, glucopyranoside, se na le phello e matla ea ho thibela motho ho tyrosinase ho feta arbutin, 'me e nkela arbutin sebaka hobane e sebetsa hantle ebile e tsitsitse.

2. Licorice Extract

Metsoako ea eona e sebetsang haholo ke liquiritin, isoliquiritin le licorice flavonoids.Liquiritin e etsa hore letlalo la melanin le aroloe ka mokhoa o ts'oanang ka ho hasanya melanin e kopaneng, 'me e fihlele phello e tšoeu;mosebetsi o ka sehloohong oa licorice flavonoids ke ho thibela mosebetsi oa tyrosinase, DHICA oxidase le dopa pigment intermutase.

Liphuputso li fumane hore lihlahisoa tsa tlhokomelo ea letlalo la bongaka tse nang le licorice extract le papain li ka thusa melasma le post-inflammatory hyperpigmentation, ka liketso tse fokolang tse mpe, 'me li na le .. le ...Khatiso ea eona ho lihlahisoa tse tšoeu ke 10% ho 40%, empa litaba tsa metsoako e sebetsang ka licorice ha li phahame mme ho hloekisa ho thata ebile ho theko e boima.

3. Chuanxiong Extract

Boithuto bo fumane hore tlhahiso ea Chuanxiong e ka thibela ts'ebetso ea tyrosinase ka nepo, e bonts'a phello ea tlholisano ea inhibitory.Setlolo sa Chuanqiong se hlahisitsoeng ka mokhoa oa motsoako oa li-emulsifiers tse fapaneng le li-thickeners tse fapaneng, lipatlisiso mabapi le katleho ea eona ea bosoeu le ts'ebetso li bontšitse hore mafura a Chuanqiong a 0.5% ~ 1.0% a na le litšobotsi tsa botsitso bo botle, ts'ebetso e phahameng le phello e ntle ea bosoeu.

4. Rhodiola Rosea Extract

Salidroside le flavonoids ke likarolo tsa eona tse ka sehloohong tse sebetsang, 'me salidroside e ka senya lipids le lera la lisele ka mahlaseli a kotsi.Sehlahisoa se ka thibela tlhahiso ea melanin le ts'ebetso ea tyrosinase, 'me ke sesebelisoa se sebetsang sa ho soeufatsa letlalo.Phuputso e fumane hore 1% le 5% ea Rhodiola rosea extract ha ea baka maikutlo a mabe 'meleng oa motho,' me ke motsoako o sebetsang oa litlolo o nang le botsitso bo phahameng 'me o na le tebello e pharaletseng ea litlolo tsa litlolo.

5. Aloin

Ke semela se tlase sa boima ba molek'hule glycoprotein e ntšitsoeng lekhalang.Haholo-holo e thibela ho thehoa ha dopaquinone ka tlhōlisano e thibelang sebaka sa dopa oxidation, 'me e finyella thibelo e se nang tlhōlisano ka tlhōlisano e thibelang li-ion tsa koporo sebakeng sa hydroxylase.Mosebetsi oa tyrosine hydroxylase.Ho feta moo, aloin e ka boela ea fokotsa ho ntšofala ha letlalo ho bakoang ke mahlaseli a ultraviolet, 'me e na le phello e ntle ea ho lokisa letlalo ka mor'a ho pepesehela letsatsi.Aloin ke hydrophilic le non-cytotoxic.Ho kopanya aloin le arbutin ho ka ntlafatsa phello ea bosoeu.

6. Semela Polyphenols

E fumaneha haholo ka har'a makhapetla, metso, makhasi le litholoana tsa limela, 'me phello ea eona e tšoeu e amana haholo le ho monya ha eona mahlaseli a ultraviolet, ho felisoa ha li-radicals tsa mahala, le ho thibela mesebetsi ea tyrosinase le peroxidase.Ellagic acid ke polyphenol ea tlhaho e ntšitsoeng lekhapetleng la kharenate, makhapetla le litholoana le meroho e fapaneng.E ka thibela ho ata ha melanocyte, ea thibela ts'ebetso ea melanocyte tyrosinase, ea fokotsa motsoako oa melanin, mahlaseli a ultraviolet a na le phello e matla ea ho monya, e ka phethang karolo ea ho sireletsa letsatsi kapa ho senya mahlaseli a mahala ka ho monya mahlaseli a ultraviolet.Polyphenol ea semela ke mofuta oa motsoako o sebetsang, o nang le tebello e pharaletseng ea nts'etsopele le ts'ebeliso ea litlolo.

Lintlha tsa lebitso:
Shaanxi Ruiwo Phytochem Co.,Ltd.
Motsamaisi oa mose ho maoatle: Jason
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Lengolo-tsoibila:jason@ruiwophytochem.com
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